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Home >> Antibodies >> NTRK3 Antibody / TrkC

NTRK3 Antibody / TrkC (RQ7984)

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  Catalog No Formulation Size Price (USD)  
Image RQ7984 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat brain and 2) mouse brain tissue lysate with NTRK3 antibody. Predicted molecular weight ~94 kDa but may be observed a higher molecular weights due to glycosylation.
Western blot testing of 1) rat brain and 2) mouse brain tissue lysate with NTRK3 antibody. Predicted molecular weight ~94 kDa but may be observed a higher molecular weights due to glycosylation.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q16288
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This NTRK3 antibody is available for research use only.
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Description

NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al.(1994) mapped the NTRK3 gene to 15q24-q25. Lamballe et al.(1991) isolated and characterized TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain; in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, Muinos-Gimeno et al.(2009) demonstrated that 5 miRNAs regulate the truncated form of NTRK3.

Application Notes

Optimal dilution of the NTRK3 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids C32-H486) was used as the immunogen for the NTRK3 antibody.

Storage

After reconstitution, the NTRK3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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