- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Titration of the NTRK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This NTRK1 antibody was produced from a mouse immunized with NTRK1 recombinant protein.
Aliquot the NTRK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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