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Home >> Antibodies >> NRG1 Antibody / Neuregulin-1

NRG1 Antibody / Neuregulin-1 [clone HRGA1-1] (V7634)

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  Catalog No Formulation Size Price (USD)  
Image V7634-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7634-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7634SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human breast carcinoma with NRG1 antibody (clone HRGA1-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
IHC staining of FFPE human breast carcinoma with NRG1 antibody (clone HRGA1-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name HRGA1-1
Purity Protein G affinity chromatography
UniProt Q02297
Localization Cell surface, cytoplasmic
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This NRG1 antibody is available for research use only.
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Description

Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Application Notes

Optimal dilution of the NRG1 antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the NRG1 antibody.

Storage

Store the NRG1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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