NR5A2 Antibody / Metabolic Signaling Transcription Factor Antibody (RQ8271)

NR5A2 Antibody Colorectal Cancer IHC. Immunohistochemistry staining of FFPE human colorectal adenocarcinoma tissue using NR5A2 antibody demonstrates prominent nuclear and cytoplasmic HRP-DAB brown staining within malignant gland-forming epithelial cells and infiltrative tumor-associated structures. The observed staining profile is consistent with expression of NR5A2 / Liver receptor homolog 1, a nuclear receptor transcription factor involved in epithelial metabolic signaling and developmental regulatory pathways. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

NR5A2 Antibody Parotid Carcinoma IHC. Immunohistochemistry staining of FFPE human parotid acinar cell carcinoma tissue using NR5A2 antibody demonstrates diffuse nuclear-associated and cytoplasmic HRP-DAB brown staining throughout malignant epithelial nests and acinar-like tumor compartments. The staining pattern supports localization of NR5A2 / Liver receptor homolog 1 within metabolically active epithelial-derived carcinoma cells linked to transcriptional regulation and endocrine-associated signaling pathways. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

NR5A2 Antibody Urothelial Tumor IHC. Immunohistochemistry staining of FFPE human bladder urothelial carcinoma tissue using NR5A2 antibody reveals heterogeneous nuclear and cytoplasmic HRP-DAB brown staining in invasive malignant urothelial cell populations separated by fibrous stromal bands. The observed staining distribution is consistent with expression of NR5A2 / Liver receptor homolog 1 in tumor-associated epithelial signaling compartments involved in metabolic and proliferative transcriptional regulation. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

NR5A2 Antibody Multi-Cell Line WB. Western blot analysis of human HepG2, A549, Caco-2, 293T, MCF7, and K562 cell lysates using NR5A2 antibody demonstrates consistent bands near 60-65 kDa across multiple epithelial and hematopoietic-derived cell lines, corresponding to the predicted molecular weight of NR5A2 / Liver receptor homolog 1. The broad expression profile supports the established role of this orphan nuclear receptor in metabolic signaling, epithelial differentiation, and transcriptional regulatory pathways.

NR5A2 Antibody Caco-2 FACS. Flow cytometry analysis of fixed and permeabilized human Caco-2 cells using NR5A2 antibody demonstrates a pronounced rightward fluorescence shift relative to isotype control, supporting intracellular expression of NR5A2 / Liver receptor homolog 1 in intestinal epithelial-derived cells. The observed staining profile is consistent with detection of this metabolic nuclear receptor transcription factor within permeabilized cellular compartments associated with gene regulatory signaling pathways. Red=cells alone, Green=isotype control, Blue=NR5A2 antibody.