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Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. [UniProt]
The stated application concentrations are suggested starting points. Titration of the Nr4a2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 164-197 from the mouse protein was used as the immunogen for the Nr4a2 antibody.
Aliquot the Nr4a2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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