- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
NOC4L Antibody [clone PCRP-NOC4L-1B2] (V9358)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V9358-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 519 | |
|
|
V9358-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 229 | |
|
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V9358SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | PCRP-NOC4L-1B2 |
| Purity | Protein A/G affinity |
| UniProt | Q9BVI4 |
| Localization | Nucleus |
| Applications | Flow cytometry : 1-2ug/million cells Immunofluorescence : 1-2ug/ml |
| Limitations | This NOC4L antibody is available for research use only. |
|
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Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
Optimal dilution of the NOC4L antibody should be determined by the researcher.
Recombinant full-length human NOC4L protein was used as the immunogen for the NOC4L antibody.
Aliquot the NOC4L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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