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  • Email: info@nsjbio.com
Home >> Antibodies >> NMDAR2B Antibody

NMDAR2B Antibody (R30239)

  Catalog No Formulation Size Price (USD)  
R30239 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of NMDAR2B antibody and Lane 1: rat brain; 2: mouse brain. Predicted molecular weight ~166kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q13224
Gene ID 2904
Applications Western blot : 0.5-1ug/ml
Limitations This NMDAR2B antibody is available for research use only.
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Description

The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene(GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B(NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the NMDAR2B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human NMDAR2B (DFYLDQFRTKENSPHW) was used as the immunogen for this NMDAR2B antibody (100% homologous in human, mouse and rat).

Storage

After reconstitution, the NMDAR2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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