NLRP3 Antibody / Inflammasome Marker (R30750)

NLRP3 Antibody Cervical Carcinoma IHC. Immunohistochemistry analysis of FFPE human squamous cell cervical carcinoma tissue stained with NLRP3 Antibody. Cytoplasmic HRP-DAB brown staining is observed throughout tumor epithelial cell populations and adjacent inflammatory-associated cellular elements, consistent with the expected expression pattern of NLRP3 / Cryopyrin, an inflammasome-associated signaling protein involved in innate immune activation, inflammatory regulation, and pyroptosis-associated cellular pathways. Tissue sections underwent HIER using pH 8 EDTA buffer prior to immunostaining.

NLRP3 Antibody Tonsil IHC. Immunohistochemistry analysis of FFPE human tonsil tissue stained with NLRP3 Antibody. Scattered cytoplasmic HRP-DAB brown staining is observed within lymphoid and immune-associated cellular populations, consistent with the expected expression profile of NLRP3 / Cryopyrin, an inflammasome-associated signaling protein involved in innate immune activation, inflammatory regulation, and cytokine maturation-associated cellular pathways. Tissue sections underwent HIER using pH 8 EDTA buffer prior to immunostaining.

NLRP3 Antibody Multi-Species WB. Western blot analysis of 1) human ThP-1, 2) rat PC-12, 3) mouse spleen, and 4) mouse RAW264.7 cell lysates using NLRP3 Antibody. Bands are detected near approximately 110-120 kDa across multiple samples, consistent with the predicted molecular weight of NLRP3 / Cryopyrin, an inflammasome-associated signaling protein involved in innate immune activation, inflammatory regulation, cytokine maturation, and pyroptosis-associated cellular pathways.

NLRP3 Antibody ThP-1 FACS. Flow cytometry analysis of fixed and permeabilized human ThP-1 cells stained with NLRP3 Antibody (blue). Cells alone are shown in red and isotype control cells in green. The distinct fluorescence shift supports detection of endogenous NLRP3 / Cryopyrin expression in ThP-1 monocytic cells, consistent with the established role of this inflammasome-associated signaling protein in innate immune activation, inflammatory regulation, and cytokine maturation-associated cellular pathways.

NLRP3 Antibody Immune Cell Line WB. Western blot analysis of rat thymus tissue, mouse thymus tissue, mouse RAW264.7 cells, and mouse J774A.1 cells using NLRP3 antibody. Strong bands are detected near approximately 110-120 kDa across multiple immune-associated samples, consistent with the predicted molecular weight of NLRP3 / Cryopyrin, an inflammasome-associated signaling protein involved in innate immune activation, inflammatory regulation, cytokine maturation, and pyroptosis-associated cellular pathways. Additional lower molecular weight bands observed in selected macrophage-associated cell lines may reflect proteolytic processing or alternative inflammasome-associated protein species.

NLRP3 Antibody Colon Cancer IHC. Immunohistochemistry analysis of FFPE human colon cancer tissue stained with NLRP3 antibody. Predominantly cytoplasmic HRP-DAB brown staining is observed within stromal inflammatory-associated cellular populations adjacent to colonic epithelial structures, consistent with the established role of NLRP3 / Cryopyrin as an inflammasome-associated signaling protein involved in innate immune activation, inflammatory regulation, and cytokine maturation-associated cellular pathways. Tissue sections underwent HIER using pH 8 EDTA buffer prior to immunostaining.