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- Tel: 858.663.9055
- Email: info@nsjbio.com
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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody.
Aliquot the NLRP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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