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- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
Optimal dilution of the NLRC4 antibody should be determined by the researcher.
Amino acids KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR of human NLRC4/CARD12 were used as the immunogen for the NLRC4 antibody.
After reconstitution, the NLRC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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