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Home >> Antibodies >> Nkx2.5 Antibody

Nkx2.5 Antibody (F52860)

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  Catalog No Formulation Size Price (USD)  
Image F52860-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52860-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of lysate from mouse stomach, rat heart tissue (left to right) using Mouse Nkx2.5 antibody at 1:1000 for each lane. Predicted molecular weight ~35 kDa, routinely observed at 35~45 kDa.
Western blot analysis of lysate from mouse stomach, rat heart tissue (left to right) using Mouse Nkx2.5 antibody at 1:1000 for each lane. Predicted molecular weight ~35 kDa, routinely observed at 35~45 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P42582
Applications Western blot : 1:1000
Limitations This Nkx2.5 antibody is available for research use only.
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Description

Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.

Application Notes

Titration of the Nkx2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This mouse Nkx2.5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 192-225 amino acids from the Central region of mouse Nkx2.5.

Storage

Aliquot the Nkx2.5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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