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Home >> Antibodies >> NKX2.5 Antibody

NKX2.5 Antibody (F45607)

  Catalog No Formulation Size Price (USD)  
Image F45607-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F45607-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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NKX2.5 antibody western blot analysis in mouse liver tissue lysate. Predicted molecular weight ~35kDa, routinely observed at 35~45kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P52952
Applications Western blot : 1:1000
Limitations This NKX2.5 antibody is available for research use only.
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Description

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Application Notes

Titration of the NKX2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 2-5 from the human protein was used as the immunogen for this NKX2.5 antibody.

Storage

Aliquot the NKX2.5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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