- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
NHERF1 Antibody / SLC9A3R1 / EBP50 [clone IIH-19] (RQ4707)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4707 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | IIH-19 |
| Purity | Affinity purified |
| UniProt | O14745 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This NHERF1 antibody is available for research use only. |
|
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The SLC9A3R1 gene encodes a sodium/hydrogen exchanger regulatory cofactor. Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (also called SLC9A3 regulator 1 and Ezrin-radixin-moesin-binding phosphoprotein 50) interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. [RefSeq]
Optimal dilution of the NHERF1 antibody should be determined by the researcher.
A synthetic peptide specific to human NHERF1 was used as the immunogen for the NHERF1 antibody.
Store the NHERF1 antibody at -20oC.
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