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- Tel: 858.663.9055
- Email: info@nsjbio.com
NF-kappa-B inhibitor zeta (I?B?) is a protein that in humans is encoded by the NFKBIZ gene.This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
Optimal dilution of the NFKBIZ antibody should be determined by the researcher.
E. coli-derived recombinant human protein (amino acids Q247-H577) was used as the immunogen for the NFKBIZ antibody.
After reconstitution, the NFKBIZ antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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