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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. The NEFH gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [RefSeq]
Optimal dilution of the NF-H antibody should be determined by the researcher.
A synthetic peptide specific to human Neurofilament Heavy / NF-H / NEFH was used as the immunogen for the NF-H antibody.
Store the NF-H antibody at -20oC.
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