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Home >> Antibodies >> Neuropeptide S Antibody

Neuropeptide S Antibody (RQ4190)

  Catalog No Formulation Size Price (USD)  
Image RQ4190 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 389
Western blot testing of 1) rat brain and 2) mouse brain lysate with Neuropeptide S antibody at 0.5ug/ml. Predicted molecular weight ~10 kDa, observed here at ~19 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P0C0P6
Applications Western Blot : 0.5-1ug/ml
Limitations This Neuropeptide S antibody is available for research use only.
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Description

Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas. NPS binds specifically to a G protein-coupled receptor, NPSR. Animal studies show that NPS suppresses anxiety and appetite, induces wakefulness and hyperactivity, including hyper-sexuality, and plays a significant role in the extinction of conditioned fear.It has also been shown to significantly enhance dopamine activity in the mesolimbic pathway, and inhibits motility and increases permeability in neurocrine fashion acting through NO in the myenteric plexus in rats and humans.

Application Notes

Optimal dilution of the Neuropeptide S antibody should be determined by the researcher.

Immunogen

Amino acids SFRNGVGTGMKKTSFQRAKS were used as the immunogen for the Neuropeptide S antibody.

Storage

After reconstitution, the Neuropeptide S antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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