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Home >> Antibodies >> Neuregulin-1 Antibody

Neuregulin-1 Antibody (R31712)

  Catalog No Formulation Size Price (USD)  
Image R31712 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Neuregulin-1 antibody and Lane 1: MCF-7; 2: SKOV; 3: 22RV1; 4: COLO320 lysate. Predicted/observed size ~70KD
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Gene ID 3084
Localization Cytoplasmic, can be nuclear and membrane
Applications Western blot : 0.5-1ug/ml
Limitations This Neuregulin-1 antibody is available for research use only.
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Description

Neuregulin-1 is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from the NRG1 gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Neuregulin-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 2-241) was used as the immunogen for this Neuregulin-1 antibody.

Storage

After reconstitution, the Neuregulin-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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