- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
NEDD9 Antibody (R31702)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R31702 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide |
| Gene ID | 4739 |
| Applications | Western blot : 0.5-1ug/ml |
| Limitations | This HEF1 antibody is available for research use only. |
|
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Neural cell expressed developmentally down regulated 9, also called Enhancer of filamentation 1 (EF1), is a protein that in humans is encoded by the NEDD9 gene. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. NEDD9 is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. It has also been reported to have a role in cancer metastasis. NEDD9 is a highly relevant cancer gene that governs metastatic potential in human melanoma. Additionally, it has been speculated that it may be an important linking element between extracellular signaling and regulation of the cytoskeleton.
The stated application concentrations are suggested starting amounts. Titration of the NEDD9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 273-E21) was used as the immunogen for this NEDD9 antibody.
After reconstitution, the NEDD9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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