NDUFB7 Antibody / NADH:ubiquinone oxidoreductase subunit B7 (RQ8099)

Description

NDUFB7 (NADH:ubiquinone oxidoreductase subunit B7) is a component of mitochondrial complex I, the first and largest enzyme of the oxidative phosphorylation (OXPHOS) system. This nuclear-encoded accessory subunit plays a structural role in stabilizing the multi-subunit complex, which is essential for transferring electrons from NADH to ubiquinone, coupled with proton translocation across the inner mitochondrial membrane.

NDUFB7 contributes to maintaining mitochondrial respiratory efficiency and ATP production. While it is not directly involved in catalysis, its presence is required for the correct assembly and stability of complex I. NDUFB7 is expressed in metabolically active tissues such as heart, brain, and skeletal muscle, making it an important focus in studies of energy metabolism, mitochondrial biology, and bioenergetic disorders.

The NDUFB7 antibody is a dependable tool for detecting endogenous NDUFB7 in applications such as western blot, immunohistochemistry, and immunofluorescence. Researchers use the NDUFB7 antibody from NSJ Bioreagents to study protein expression, evaluate mitochondrial integrity, and investigate complex I function under physiological and experimental conditions. With strong specificity and consistent results, the NDUFB7 antibody supports detailed exploration of mitochondrial structure, respiratory chain assembly, and cellular energy homeostasis.

Application Notes

Optimal dilution of the NDUFB7 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids M1-R98) was used as the immunogen for the NDUFB7 antibody.

Storage

After reconstitution, the NDUFB7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.