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- Tel: 858.663.9055
- Email: info@nsjbio.com
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NAT10 has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
The stated application concentrations are suggested starting points. Titration of the NAT10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 146-178 from human NAT10 was used as the immunogen for the NAT10 antibody.
Aliquot the NAT10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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