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Home >> Antibodies >> NALP12 Antibody (NLRP12)

NALP12 Antibody (NLRP12) [clone 228CT4.1.3] (F40258)

  Catalog No Formulation Size Price (USD)  
Image F40258-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40258-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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NALP12 antibody western blot analysis in mouse brain tissue lysate. Predicted molecular weight: ~119kDa, routinely observed at 100~119kDa.
Availability 1-3 business days
Species Reactivity Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgM, k
Clone Name 228CT4.1.3
Purity Purified
UniProt P59046
Applications Western blot : 1:500-1:1500
Limitations This NALP12 antibody is available for research use only.
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Description

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Application Notes

The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.

Storage

Store at 4oC for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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