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Home >> Antibodies >> Myxovirus resistance protein 1 Antibody / MX1 / MxA

Myxovirus resistance protein 1 Antibody / MX1 / MxA (RQ7192)

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  Catalog No Formulation Size Price (USD)  
Image RQ7192 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human HeLa, 2) human A549 and 3) mouse lung tissue lysate with MX1 antibody. Predicted molecular weight ~76 kDa.
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Western blot testing of 1) human HeLa, 2) human A549 and 3) mouse lung tissue lysate with MX1 antibody. Predicted molecular weight ~76 kDa.
Flow cytometry testing of human RT4 cells with MX1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MX1 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P20591
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Myxovirus resistance protein 1 antibody is available for research use only.
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Description

Interferon-induced GTP-binding protein Mx1, also called Myxovirus resistance protein 1, Myxoma resistance protein 1 and MxA, is a protein that in humans is encoded by the MX1 gene. This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the Myxovirus resistance protein 1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids N116-H595) was used as the immunogen for the Myxovirus resistance protein 1 antibody.

Storage

After reconstitution, the Myxovirus resistance protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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