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Home >> Antibodies >> Myostatin Antibody / GDF8

Myostatin Antibody / GDF8 (F47925)

  Catalog No Formulation Size Price (USD)  
Image F47925-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 439
Image
F47925-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 205
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Myostatin Antibody Skeletal Muscle IHC. Immunohistochemistry analysis of FFPE human skeletal muscle tissue stained with Myostatin antibody demonstrates diffuse cytoplasmic HRP-DAB brown staining within skeletal myofiber-associated cellular structures, consistent with expression of Myostatin / MSTN, a transforming growth factor beta family member involved in negative regulation of skeletal muscle growth and myogenic differentiation pathways. The observed staining profile aligns with the established role of Myostatin in muscle mass regulation, myofiber homeostasis, and skeletal muscle remodeling biology.
Myostatin Antibody Skeletal Muscle WB. Western blot analysis of human skeletal muscle tissue lysate using Myostatin antibody demonstrates a distinct band at approximately 43 kDa, consistent with the predicted molecular weight of Myostatin / MSTN, a transforming growth factor beta family member involved in negative regulation of skeletal muscle growth and myogenic differentiation pathways. The observed expression pattern aligns with the established role of Myostatin in skeletal muscle homeostasis, myofiber remodeling, and muscle mass regulatory signaling.
Myostatin Antibody Heart WB. Western blot analysis of human heart tissue lysate using Myostatin antibody demonstrates a distinct band at approximately 43 kDa, consistent with the predicted molecular weight of Myostatin / MSTN, a transforming growth factor beta family member involved in regulation of muscle growth and myogenic signaling pathways. The observed cardiac tissue expression profile aligns with the known role of Myostatin in muscle homeostasis, contractile tissue remodeling, and metabolic regulation within striated muscle-associated cellular environments.
Myostatin Antibody WB. Western blot testing of human 1) HeLa and 2) K562 cell lysate with Myostatin antibody. Predicted molecular weight ~43 kDa.
Myostatin Antibody Mouse Liver WB. Western blot testing of mouse liver tissue lysate with Myostatin antibody. Predicted molecular weight ~43 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Bovine, Pig, Primate
Format Purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O14793
Applications Western Blot : 1:1000
IHC (Paraffin) : 1:50
Limitations This Myostatin antibody is available for research use only.
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Description

Myostatin Antibody specifically detects Myostatin / GDF8, a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Explore our Signal Transduction Antibodies page to discover additional regulatory proteins involved in cellular signaling, transcriptional control, differentiation pathways, and oncogenic signaling networks.

Application Notes

Titration of the Myostatin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 9-38 from the human protein was used as the immunogen for this Myostatin antibody.

Storage

Aliquot the Myostatin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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