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Home >> Antibodies >> Myostatin Antibody / GDF8

Myostatin Antibody / GDF8 (F47925)

  Catalog No Formulation Size Price (USD)  
Image F47925-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F47925-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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IHC analysis of FFPE human skeletal muscle tissue stained with Myostatin antibody
Western blot testing of human skeletal muscle tissue lysate with Myostatin antibody. Predicted molecular weight ~43 kDa.
Western blot testing of human heart tissue lysate with Myostatin antibody. Predicted molecular weight ~43 kDa.
Western blot testing of human 1) HeLa and 2) K562 cell lysate with Myostatin antibody. Predicted molecular weight ~43 kDa.
Western blot testing of mouse liver tissue lysate with Myostatin antibody. Predicted molecular weight ~43 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Bovine, Pig, Primate
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O14793
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50
Limitations This Myostatin antibody is available for research use only.
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  • Applications : WB
    Reactivity : Human, Mouse, Rat

Description

GDF8/Myostatin is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Application Notes

Titration of the Myostatin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 9-38 from the human protein was used as the immunogen for this Myostatin antibody.

Storage

Aliquot the Myostatin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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