• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> MyD88 Antibody

MyD88 Antibody (R30745)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image R30745 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Western blot testing of MyD88 antibody and Lane 1: rat spleen; 2: rat thymus; 3: Jurkat; 4: Raji cell lysate. Predicted molecular weight: 33 kDa
›
Western blot testing of MyD88 antibody and Lane 1: rat spleen; 2: rat thymus; 3: Jurkat; 4: Raji cell lysate. Predicted molecular weight: 33 kDa
IHC-P: MyD88 antibody testing of human tonsil tissue
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q99836
Localization Cytoplasmic
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This MyD88 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : WB, IHC
    Reactivity : Human
    Recrabbitmono
  • Applications : WB
    Reactivity : Human, Mouse
  • Applications : WB, IHC-P, IF, FACS
    Reactivity : Human, Mouse, Rat
  • Applications : WB, IHC, ELISA (peptide), EIA
    Reactivity : Human
    Pred. Reactivity : Dog, Mouse, Rat
  • Applications : WB, IHC, ELISA (peptide)
    Reactivity : Human
    Pred. Reactivity : Dog, Mouse, Rat
  • Applications : WB
    Reactivity : Mouse, Rat
  • Applications : WB
    Reactivity : Rat
  • Applications : WB, IHC, FACS, ELISA
    Reactivity : Human, Mouse
    Pred. Reactivity : Primate
  • Applications : WB, IHC-P, FACS, Direct ELISA
    Reactivity : Human

Description

Myeloid differentiation primary response gene 88 is a protein that in humans is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors(IL1Rs). It a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 andToll-like receptorsignaling pathways. Qverexpression causes an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of the protein has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MyD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.

Application Notes

The stated application concentrations are suggested starting points. Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the middle region of human MyD88 (FVQEMIRQLEQTNYR) was used as the immunogen for this MyD88 antibody.

Storage

After reconstitution, the MyD88 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all MyD88 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.