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Home >> Antibodies >> MyD88 Antibody

MyD88 Antibody (F51176)

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  Catalog No Formulation Size Price (USD)  
Image F51176-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F51176-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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IHC analysis of FFPE human lung carcinoma stained with MyD88 antibody
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IHC analysis of FFPE human lung carcinoma stained with MyD88 antibody
Western blot analysis of MyD88 antibody and HepG2 lysate. Predicted molecular weight: 33 kDa
Western blot analysis of MyD88 antibody and mouse lung tissue lysate. Predicted molecular weight: 33 kDa
MyD88 antibody flow cytometric analysis of NCI-H460 cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
  • IHC analysis of FFPE human lung carcinoma stained with MyD88 antibody
  • Western blot analysis of MyD88 antibody and HepG2 lysate. Predicted molecular weight: 33 kDa
  • Western blot analysis of MyD88 antibody and mouse lung tissue lysate. Predicted molecular weight: 33 kDa
  • MyD88 antibody flow cytometric analysis of NCI-H460 cells (green) compared to a <a href=negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis." title="MyD88 antibody flow cytometric analysis of NCI-H460 cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis." onClick="showhideiamges('image4','imagelargedata4',4,4)">
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Primate
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q99836
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Flow Cytometry : 1:10-1:50
Limitations This MyD88 antibody is available for research use only.
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Description

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.

Application Notes

Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.

Storage

Aliquot the MyD88 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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