MX1 Antibody / Myxovirus resistance protein 1 / MxA [clone MX1/7527] (V4843)

MX1 Antibody Ovarian Cancer IHC. Immunohistochemical staining of FFPE human ovarian cancer tissue using MX1 Antibody / Antiviral Response Protein Antibody (clone MX1/7527) demonstrates strong cytoplasmic and membranous HRP-DAB brown staining throughout malignant epithelial tumor cells. MX1 (Myxovirus Resistance Protein 1) is an interferon-inducible dynamin-like GTPase that functions as a key mediator of innate antiviral immunity and host defense. As a downstream effector of interferon signaling pathways, MX1 contributes to restriction of viral replication and serves as a widely utilized marker of interferon-responsive cellular activity. The observed staining pattern is consistent with expression of MX1 within neoplastic epithelial cells and supports the utility of this antibody for immunohistochemical detection of antiviral response proteins and interferon-regulated pathways in human tissues. Inset: PBS was used in place of the primary antibody as a negative control. HIER: boil tissue sections in pH 9, 10 mM Tris with 1 mM EDTA for 20 minutes and allow to cool before testing.

MX1 Antibody Human Kidney IHC. Immunohistochemical staining of FFPE human kidney tissue using MX1 Antibody / Antiviral Response Protein Antibody (clone MX1/7527) demonstrates moderate to strong granular cytoplasmic HRP-DAB brown staining throughout renal tubular epithelial cells, with comparatively limited staining within glomerular structures. MX1 (Myxovirus Resistance Protein 1) is an interferon-inducible dynamin-like GTPase that functions as a key mediator of innate antiviral immunity and host defense. As a downstream effector of interferon signaling pathways, MX1 contributes to antiviral cellular responses and serves as a widely utilized marker of interferon-regulated activity. The observed tubular staining pattern is consistent with expression of MX1 in epithelial cell populations and supports the utility of this antibody for immunohistochemical detection of interferon-responsive proteins in human tissues. Inset: PBS was used in place of the primary antibody as a negative control. HIER: boil tissue sections in pH 9, 10 mM Tris with 1 mM EDTA for 20 minutes and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free MX1 antibody (clone MX1/7527) as confirmation of integrity and purity.