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Home >> Antibodies >> Mucin 13 Antibody / MUC13

Mucin 13 Antibody / MUC13 [clone MUC13/13113] (V5779)

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  Catalog No Formulation Size Price (USD)  
Image V5779-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5779-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5779SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human small intestine tissue with Mucin 13 antibody (clone MUC13/13113). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human small intestine tissue with Mucin 13 antibody (clone MUC13/13113). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Mucin 13 antibody (clone MUC13/13113) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name MUC13/13113
Purity Protein A affinity
UniProt Q9H3R2
Localization Cell membrane, Cytoplasm, Secreted
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Mucin 13 antibody is available for research use only.
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Description

Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

Application Notes

Optimal dilution of the Mucin 13 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 100-300 from human Mucin 13 protein was used as the immunogen for the Mucin 13 antibody.

Storage

Aliquot the Mucin 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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