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Home >> Antibodies >> Mtnd2 Antibody / NADH2

Mtnd2 Antibody / NADH2 (RQ5994)

  Catalog No Formulation Size Price (USD)  
Image RQ5994 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat brain and 2) mouse brain tissue lysate with Mtnd2 antibody. Predicted molecular weight ~39 kDa.
Flow cytometry testing of rat RH35 cells with Mtnd2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Mtnd2 antibody.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P11662
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Limitations This Mtnd2 antibody is available for research use only.
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  • Applications : WB, FACS
    Reactivity : Mouse, Rat

Description

Mitochondrially encoded NADH dehydrogenase 2 is protein that in humans is encoded by the mitochondrial gene MT-ND2 gene. The ND2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variants of MT-ND2 are associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), Leigh's syndrome (LS), Leber's hereditary optic neuropathy (LHON) and increases in adult BMI.

Application Notes

Optimal dilution of the Mtnd2 antibody should be determined by the researcher.

Immunogen

Amino acids LEMSLLAIIPLLANKKSPRS from the rat protein were used as the immunogen for the Mtnd2 antibody.

Storage

After reconstitution, the Mtnd2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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