- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
MT-ND3 Antibody / NADH-ubiquinone oxidoreductase chain 3 (F55133)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F55133-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 429 | |
|
|
F55133-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 199 |
| Availability | 1-2 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P03897 |
| Applications | Western Blot : 1:500-1:1000 Flow Cytometry : 1:10-1:50 per million cells in 0.1ml |
| Limitations | This MT-ND3 antibody is available for research use only. |
|
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MT-ND3 is a critical subunit of complex I, acting as a catalyst in the transfer of electrons from NADH to ubiquinone. This process is essential for generating the proton gradient necessary for ATP production. Without MT-ND3, the electron transport chain would not be able to function properly, leading to a decrease in ATP production and ultimately, cellular dysfunction. Research has shown that mutations in the gene encoding MT-ND3 can lead to mitochondrial diseases and a range of health problems, including muscle weakness, neurological disorders, and even premature aging.
The stated application concentrations are suggested starting amounts. Titration of the MT-ND3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 10-38 from the human protein was used as the immunogen for this MT-ND3 antibody.
Store at 4oC for up to one month. For long term, aliquot the MT-ND3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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