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- Tel: 858.663.9055
- Email: info@nsjbio.com
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MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
Titration of the MST1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 385-415 from the human protein was used as the immunogen for this MST1 antibody.
Aliquot the MST1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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