CD206 Antibody / Macrophage Mannose Receptor Antibody (RQ8722)

CD206 Antibody Human Tonsil IF. Immunofluorescent staining of FFPE human tonsil tissue using CD206 Antibody / Macrophage Mannose Receptor Antibody demonstrates strong red fluorescence within scattered immune cell populations distributed throughout the lymphoid tissue. The staining pattern is consistent with expression of CD206 (MRC1), a C-type lectin receptor involved in carbohydrate recognition, endocytosis, antigen processing, and macrophage-mediated immune regulation. Positive cells are observed within the tonsillar immune microenvironment, supporting the established role of CD206 as a marker of macrophages and specialized antigen-presenting cell populations. DAPI nuclear counterstain (blue) identifies cell nuclei and tissue architecture. HIER: steam section in pH8 EDTA buffer for 20 min.

CD206 Antibody Mouse Liver IF. Immunofluorescent staining of FFPE mouse liver tissue using CD206 Antibody / Macrophage Mannose Receptor Antibody demonstrates strong red fluorescence within scattered hepatic immune cell populations and sinusoidal-associated cells throughout the liver parenchyma. The staining pattern is consistent with expression of CD206 (MRC1), a C-type lectin receptor involved in carbohydrate recognition, receptor-mediated endocytosis, antigen processing, and macrophage-mediated immune regulation. Positive immunoreactivity is compatible with resident macrophage populations and other antigen-presenting cells that contribute to hepatic immune surveillance and tissue homeostasis. DAPI nuclear counterstain (blue) identifies cell nuclei and tissue architecture. HIER: steam section in pH8 EDTA buffer for 20 min.

CD206 Antibody Rat Liver IHC. Immunohistochemical staining of FFPE rat liver tissue using CD206 Antibody / Macrophage Mannose Receptor Antibody demonstrates widespread cytoplasmic and membranous HRP-DAB brown staining throughout hepatic sinusoidal-associated cells and scattered immune cell populations. The staining pattern is consistent with expression of CD206 (MRC1), a C-type lectin receptor involved in carbohydrate recognition, receptor-mediated endocytosis, antigen processing, and macrophage-mediated immune regulation. Positive immunoreactivity is compatible with resident hepatic macrophages and other antigen-presenting cell populations that contribute to liver immune surveillance, clearance of glycosylated ligands, and maintenance of tissue homeostasis. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

CD206 Antibody Mouse Liver IHC. Immunohistochemical staining of FFPE mouse liver tissue using CD206 Antibody / Macrophage Mannose Receptor Antibody demonstrates distinct cytoplasmic and membranous HRP-DAB brown staining within sinusoidal-associated cells and scattered hepatic immune cell populations. The staining pattern is consistent with expression of CD206 (MRC1), a C-type lectin receptor that mediates carbohydrate recognition, receptor-mediated endocytosis, antigen uptake, and macrophage-associated immune functions. Positive immunoreactivity is observed throughout the liver parenchyma and is compatible with resident macrophage populations involved in immune surveillance, clearance of extracellular material, and maintenance of hepatic homeostasis. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

CD206 Antibody Human Tonsil IHC. Immunohistochemical staining of FFPE human tonsil tissue using CD206 Antibody / Macrophage Mannose Receptor Antibody demonstrates distinct cytoplasmic and membranous HRP-DAB brown staining within scattered immune cell populations distributed throughout the lymphoid tissue. The staining pattern is consistent with expression of CD206 (MRC1), a C-type lectin receptor involved in carbohydrate recognition, receptor-mediated endocytosis, antigen processing, and macrophage-mediated immune regulation. Positive immunoreactivity is observed in cells compatible with macrophage and antigen-presenting cell populations within the tonsillar microenvironment, supporting the established role of CD206 as a marker of innate immune cell function and tissue immune surveillance. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

CD206 Antibody Human Liver Cancer IHC. Immunohistochemical staining of FFPE human liver cancer tissue using CD206 Antibody / Macrophage Mannose Receptor Antibody demonstrates widespread cytoplasmic and membranous HRP-DAB brown staining throughout the tumor microenvironment, including scattered immune cell populations and stromal-associated elements. The staining pattern is consistent with expression of CD206 (MRC1), a C-type lectin receptor involved in carbohydrate recognition, receptor-mediated endocytosis, antigen processing, and macrophage-mediated immune regulation. Positive immunoreactivity is compatible with tumor-associated macrophages and other antigen-presenting cell populations that contribute to immune modulation, tissue remodeling, and cellular communication within the hepatic tumor microenvironment. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

CD206 Antibody Human Monkey Mouse Rat WB. Western blot analysis of 1) rat lung, 2) mouse lung, 3) human liver, and 4) monkey lung tissue lysates using CD206 Antibody / Macrophage Mannose Receptor Antibody. A strong immunoreactive band is detected at approximately 180-200 kDa in all samples, consistent with expression of CD206 (MRC1), a heavily glycosylated C-type lectin receptor involved in carbohydrate recognition, receptor-mediated endocytosis, antigen processing, and macrophage-mediated immune regulation. Although the predicted molecular weight of MRC1 is approximately 166 kDa, the protein commonly migrates at a higher apparent molecular weight due to extensive N-linked glycosylation. The consistent detection of CD206 across multiple species demonstrates the broad reactivity of this antibody and supports its utility for western blot analysis of endogenous MRC1 expression. Predicted molecular weight: ~166 kDa. Observed molecular weight: ~180-200 kDa.