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- Email: info@nsjbio.com
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Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
Optimal dilution of the MR1 antibody should be determined by the researcher.
Amino acids R23-D269 from the human protein were used as the immunogen for the MR1 antibody.
After reconstitution, the MR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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