- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
MPO Antibody Rabbit Monoclonal MPO/8631R / Myeloperoxidase Antibody [clone MPO/8631R] (V4526)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V4526-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V4526-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
|
V4526SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | MPO/8631R |
| Purity | Protein A/G affinity |
| UniProt | P05164 |
| Localization | Cytoplasm |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This MPO antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Myeloperoxidase (MPO) is a heme-containing peroxidase enzyme encoded by the MPO gene and is one of the most abundant proteins stored in the azurophilic granules of neutrophils. MPO plays a central role in innate immune defense by catalyzing the production of reactive oxidant species during the respiratory burst of activated phagocytes. MPO Antibody Rabbit Monoclonal MPO/8631R recognizes Myeloperoxidase / MPO and supports detection of this important enzyme in studies examining neutrophil biology, inflammatory responses, and myeloid cell function. Through its catalytic activity, MPO converts hydrogen peroxide and chloride ions into hypochlorous acid, a potent antimicrobial oxidant capable of destroying engulfed microorganisms.
Myeloperoxidase antibody, also referred to as MPO antibody or myeloid peroxidase antibody in the literature, detects a granule-associated enzyme that is highly enriched in neutrophils and present in monocytes and immature myeloid precursors. Because MPO expression is strongly associated with granulocytic lineage cells, the protein is widely used as a marker for identifying neutrophils and studying inflammatory infiltrates in tissues. MPO Antibody Rabbit Monoclonal MPO/8631R enables analysis of MPO-positive cells in biological samples where immune cell recruitment and innate immune responses are being investigated.
Within neutrophils, MPO is stored in cytoplasmic azurophilic granules and released during cell activation and degranulation. In addition to microbial killing, MPO-derived oxidants contribute to inflammatory signaling and oxidative modification of biological molecules. These oxidative reactions can influence immune regulation as well as tissue injury during chronic inflammation. As a result, MPO has been widely studied in disease processes including cardiovascular disease, autoimmune disorders, infection, and tumor-associated inflammation.
Detection of Myeloperoxidase using MPO Antibody Rabbit Monoclonal MPO/8631R allows researchers to identify granulocytic cells and evaluate neutrophil involvement in inflammatory responses. Analysis of MPO expression can provide insight into immune cell recruitment, granulocyte activation, and oxidative immune mechanisms in both normal and pathological tissues. This rabbit monoclonal antibody provides a defined reagent for studies investigating innate immune biology, inflammatory disease pathways, and myeloid lineage cell activity.
Optimal dilution of the MPO Antibody Rabbit Monoclonal MPO/8631R should be determined by the researcher.
A recombinant fragment of human MPO protein was used as the immunogen for the MPO antibody.
Aliquot the MPO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Myeloperoxidase antibody, MPO antibody, Myeloid peroxidase antibody, Neutrophil MPO antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
