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Home >> Antibodies >> MPO Antibody

MPO Antibody (F42682)

  Catalog No Formulation Size Price (USD)  
Image F42682-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
Image
F42682-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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MPO antibody western blot analysis in NCI-H460 lysate. Expected molecular weight: 59-64 kDa (alpha chain, may be observed at higher molecular weights due to glycosylation), 150+ kDa (glycosylated mature form).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P05164
Applications Western Blot : 1:1000
Limitations This MPO antibody is available for research use only.
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Description

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].

Explore our Myeloperoxidase Antibody / Neutrophil Marker Antibody page for additional validation data and applications involving neutrophil identification, myeloid lineage analysis, and innate immune cell detection.

Application Notes

Titration of the MPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 548-575 from the human protein was used as the immunogen for this MPO antibody.

Storage

Aliquot the MPO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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