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Home >> Antibodies >> MMP9 Antibody / Matrix metalloproteinase-9

MMP9 Antibody / Matrix metalloproteinase-9 [clone BCD-13] (RQ5435)

  Catalog No Formulation Size Price (USD)  
Image RQ5435 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing with MMP9 antibody. Expected molecular weight: ~92 kDa (precursor), 67-80 kDa (mature).
IHC staining of FFPE human colon cancer with MMP9 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-2 weeks
Species Reactivity Human, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name BCD-13
Purity Affinity purified
UniProt P14780
Localization Cytoplasmic, nuclear, secreted
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This MMP9 antibody is available for research use only.
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Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [RefSeq]

Application Notes

Optimal dilution of the MMP9 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human MMP9 was used as the immunogen for the MMP9 antibody.

Storage

Store the MMP9 antibody at -20oC.

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