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Home >> Antibodies >> MMP9 Antibody

MMP9 Antibody (R30424)

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  Catalog No Formulation Size Price (USD)  
Image R30424 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of MMP9 antibody and Lane 1: rat embryo; 2: MM453; 3: HeLa; 4: SMMC-7721; 5: Jurkat; 6: HT1080. Predicted molecular weight: 92/67-80 kDa (precursor/mature forms).
Western blot testing of MMP9 antibody and Lane 1: rat embryo; 2: MM453; 3: HeLa; 4: SMMC-7721; 5: Jurkat; 6: HT1080. Predicted molecular weight: 92/67-80 kDa (precursor/mature forms).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P14780
Localization Cytoplasmic, nuclear, secreted
Applications Western blot : 0.5-1ug/ml
Limitations This MMP9 antibody is available for research use only.
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Description

Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is an enzyme that in humans is encoded by the MMP9 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the MMP9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human MMP9(NQVDQVGYVTYDILQCP) was used as the immunogen for this MMP9 antibody.

Storage

After reconstitution, the MMP9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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