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Home >> Antibodies >> MMP3 Antibody

MMP3 Antibody [clone BBO-13] (RQ5214)

  Catalog No Formulation Size Price (USD)  
Image RQ5214 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human recombinant protein with MMP3 antibody. Predicted molecular weight ~54 kDa.
IHC staining of FFPE human liver cancer with MMP3 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name BBO-13
Purity Affinity purified
UniProt P08254
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This MMP3 antibody is available for research use only.
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Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The MMP3 gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. [RefSeq]

Application Notes

Optimal dilution of the MMP3 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human MMP3 was used as the immunogen for the MMP3 antibody.

Storage

Store the MMP3 antibody at -20oC.

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