MMP1 Antibody / Interstitial Collagenase Antibody (RQ5503)

MMP1 Antibody U-2 OS Cell IF. Immunofluorescence analysis of FFPE human U-2 OS cells using MMP1 Antibody / Interstitial Collagenase Antibody. Heat induced antigen retrieval was performed by boiling sections in pH 6 citrate buffer for 20 minutes prior to staining. MMP1 expression is shown in green with DAPI nuclear counterstain shown in blue. Predominantly cytoplasmic staining is observed, consistent with intracellular synthesis and processing of this secreted extracellular matrix remodeling enzyme. These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying extracellular matrix remodeling, collagen degradation and cancer-associated tissue remodeling pathways.

MMP1 Antibody Human Tissue and Cancer Cell WB. Western blot analysis using MMP1 Antibody / Interstitial Collagenase Antibody. Lane 1: human placenta; Lane 2: human Caco-2 cells; Lane 3: human K562 cells; Lane 4: human U-2 OS cells; Lane 5: human MCF7 cells. A specific band is detected at approximately 54 kDa, consistent with the predicted molecular weight of the MMP1 proenzyme (pro-MMP1). These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying extracellular matrix remodeling, interstitial collagenase expression and cancer-associated tissue remodeling pathways.

MMP1 Antibody PC-3 Cell FACS. Flow cytometry analysis of human PC-3 cells using MMP1 Antibody / Interstitial Collagenase Antibody at 1 ug/million cells. Cells were blocked with goat sera prior to staining. The blue histogram represents MMP1 antibody staining, the green histogram represents the isotype control and the red histogram represents cells alone. A distinct rightward shift of the antibody-stained population demonstrates specific detection of MMP1 expression in PC-3 cells. These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying extracellular matrix remodeling, interstitial collagenase expression and cancer-associated tissue remodeling pathways.

MMP1 Antibody Human Intestinal Cancer IHC. Immunohistochemistry analysis of FFPE human intestinal cancer tissue using MMP1 Antibody / Interstitial Collagenase Antibody. Heat induced antigen retrieval was performed by boiling tissue sections in pH 6 citrate buffer for 20 minutes prior to staining. Strong cytoplasmic and membranous staining is observed in malignant epithelial cells, consistent with MMP1 expression in tumors undergoing extracellular matrix remodeling. These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying interstitial collagenase expression, tumor invasion and cancer-associated extracellular matrix remodeling.

MMP1 Antibody Human Breast Cancer IHC. Immunohistochemistry analysis of FFPE human breast cancer tissue using MMP1 Antibody / Interstitial Collagenase Antibody. Heat induced antigen retrieval was performed by boiling tissue sections in pH 6 citrate buffer for 20 minutes prior to staining. Strong cytoplasmic and membranous staining is observed in malignant epithelial cells, consistent with MMP1 expression associated with extracellular matrix remodeling and tumor progression. These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying interstitial collagenase expression, breast cancer biology and cancer-associated tissue remodeling.

MMP1 Antibody Human Placenta IHC. Immunohistochemistry analysis of FFPE human placenta tissue using MMP1 Antibody / Interstitial Collagenase Antibody. Heat induced antigen retrieval was performed by boiling tissue sections in pH 6 citrate buffer for 20 minutes prior to staining. Strong staining is observed in trophoblast cells, consistent with MMP1 expression in placental tissue remodeling and extracellular matrix turnover. These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying interstitial collagenase expression, placental biology and extracellular matrix remodeling.

MMP1 Antibody Human, Rat and Mouse WB. Western blot analysis using MMP1 Antibody / Interstitial Collagenase Antibody. Lane 1: human placenta; Lane 2: human Caco-2 cells; Lane 3: human K562 cells; Lane 4: human U-2 OS cells; Lane 5: human MCF-7 cells; Lane 6: rat RH35 cells; Lane 7: mouse Hepa1-6 cells. A specific band is detected at approximately 54 kDa in all samples, consistent with the predicted molecular weight of the MMP1 proenzyme (pro-MMP1). These results support the use of MMP1 Antibody / Interstitial Collagenase Antibody for studying extracellular matrix remodeling, interstitial collagenase expression and cancer-associated tissue remodeling across human, rat and mouse samples.