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Home >> Antibodies >> MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region)

MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region) (F54182)

  Catalog No Formulation Size Price (USD)  
Image F54182-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F54182-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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Western blot testing of human lung tissue lysate with MKS1 antibody at 1:2000. Predicted molecular weight ~65 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NXB0
Applications Western Blot : 1:1000-1:2000
Limitations This MKS1 antibody is available for research use only.
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Description

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

Application Notes

The stated application concentrations are suggested starting points. Titration of the MKS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 38-72 from human MKS1 was used as the immunogen for the MKS1 antibody.

Storage

Aliquot the MKS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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