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Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe2+, is then probably delivered to ferrochelatase to catalyze Fe2+ incorporation into protoprophyrin IX to make heme (By similarity). [UniProt]
The stated application concentrations are suggested starting points. Titration of the Mitoferrin-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 309-338 from the human protein was used as the immunogen for the Mitoferrin-1 antibody.
Aliquot the Mitoferrin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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