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- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
Optimal dilution of the MICB antibody should be determined by the researcher.
Amino acids AEPHSLRYNLMVLSQDESVQSGFLAE of human MICB were used as the immunogen for the MICB antibody.
After reconstitution, the MICB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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