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Home >> Antibodies >> mGluR2 Antibody / Metabotropic Glutamate Receptor 2 / GRM2 (C-Terminal Region)

mGluR2 Antibody / Metabotropic Glutamate Receptor 2 / GRM2 (C-Terminal Region) (F54174)

  Catalog No Formulation Size Price (USD)  
Image F54174-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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Western blot testing of human cerebellum lysate with mGluR2 antibody at 1:2000. Predicted molecular weight ~96 kDa, routinely observed at 110-120 kDa (monomer) and 220-240 kDa (dimer).
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q14416
Applications Western Blot : 1:1000-1:2000
Limitations This mGluR2 antibody is available for research use only.
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Description

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Application Notes

The stated application concentrations are suggested starting points. Titration of the mGluR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 681-715 from human GRM2 was used as the immunogen for the mGluR2 antibody.

Storage

Aliquot the mGluR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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