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Home >> Antibodies >> MFN2 Antibody

MFN2 Antibody (F51381)

  Catalog No Formulation Size Price (USD)  
Image F51381-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F51381-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC analysis of FFPE mouse kidney stained with MFN2 antibody
Western blot analysis of MFN2 antibody and K562 lysate
MFN2 antibody flow cytometric analysis of K562 cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt O95140
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This MFN2 antibody is available for research use only.
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Description

MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.

Application Notes

Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 447-476 from the human protein was used as the immunogen for this MFN2 antibody.

Storage

Aliquot the MFN2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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