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Home >> Antibodies >> MET Antibody (HGFR)

MET Antibody (HGFR) [clone 6AT1785] (F40181)

  Catalog No Formulation Size Price (USD)  
Image F40181-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40181-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Fluorescent confocal image of HepG2 cells stained with HGFR / MET antibody. Note the highly specific localization of the MET immunosignal to the cytoplasm.
MET antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 6AT1785
Purity Purified
UniProt P08581
Applications Immunofluorescence : 1:200
IHC (Paraffin) : 1:10-1:50
Limitations This MET antibody (HGFR) is available for research use only.
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Description

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Application Notes

Titration of the MET antibody (HGFR) may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.

Storage

Aliquot the MET antibody (HGFR) and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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