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Home >> Antibodies >> MEAK7 Antibody / TLDC1 / KIAA1609

MEAK7 Antibody / TLDC1 / KIAA1609 (F54549)

  Catalog No Formulation Size Price (USD)  
Image F54549-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54549-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC testing of FFPE human uterus tissue with MEAK7 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of human DU145 cell lysate with MEAK7 antibody. Predicted molecular weight ~51 kDa.
Western blot testing of mouse NIH 3T3 cell lysate with MEAK7 antibody. Predicted molecular weight ~51 kDa.
Flow cytometry testing of mouse NIH 3T3 cells with MEAK7 antibody; Blue=isotype control, Green= MEAK7 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt Q6P9B6
Applications Flow cytometry : 1:25 (1x10e6 cells)
Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:25
Limitations This MEAK7 antibody is available for research use only.
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Description

Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome. [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the MEAK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 426-456 from the human protein was used as the immunogen for the MEAK7 antibody .

Storage

Aliquot the MEAK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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