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Home >> Antibodies >> MEAF6 Antibody

MEAF6 Antibody (F53907)

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  Catalog No Formulation Size Price (USD)  
Image F53907-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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Western blot testing of human PC-3 cell lysate with MEAF6 antibody at 1:2000. Predicted molecular weight: 22 kDa.
Western blot testing of human PC-3 cell lysate with MEAF6 antibody at 1:2000. Predicted molecular weight: 22 kDa.
F53907-0.05ML
Titration of the MEAF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This MEAF6 antibody is available for research use only.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9HAF1
Applications Western blot : 1:1000-2000
Limitations This MEAF6 antibody is available for research use only.
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Description

MYST/Esa1-associated factor 6 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.

Application Notes

Titration of the MEAF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 120-154 from the human protein was used as the immunogen for the MEAF6 antibody.

Storage

Aliquot the MEAF6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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