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Home >> Antibodies >> Mcad Antibody / ACADM

Mcad Antibody / ACADM [clone COE-1] (RQ5361)

  Catalog No Formulation Size Price (USD)  
Image RQ5361 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of human 1) HeLa and 2) K562 cell lysate with Mcad antibody. Predicted molecular weight ~46 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name COE-1
Purity Affinity purified
UniProt P11310
Applications Western blot : 1:500-1:2000
Limitations This Mcad antibody is available for research use only.
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Description

The ACADM gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [RefSeq]

Application Notes

Optimal dilution of the Mcad antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Mcad / ACADM was used as the immunogen for the Mcad antibody.

Storage

Store the Mcad antibody at -20oC.

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