MYC Associated Factor X Antibody | MAX Antibody

	Catalog No	Formulation	Size	Price (USD)
	R33757-100UG	0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide	100 ug	475
Formulation

MYC Associated Factor X Antibody Human Jurkat WB. Western blot analysis was performed using MAX Antibody on human Jurkat cell lysate. A prominent immunoreactive band is detected at approximately 21–22 kDa, with MAX also reported to migrate as a lower molecular weight form at approximately 16–17 kDa depending on isoform expression and post-translational processing. The observed signal is consistent with the expected migration pattern of MYC Associated Factor X (MAX). This MYC Associated Factor X Antibody / MAX Antibody is well suited for Western blot studies of MYC signaling, transcription factor complex formation, gene regulation, and cell cycle control.

Availability	1-3 business days
Species Reactivity	Human, Mouse, Rat
Predicted Reactivity	Dog, Cow
Format	Antigen affinity purified
Host	Goat
Clonality	Polyclonal (goat origin)
Isotype	Goat Ig
Purity	Antigen affinity
Gene ID	4149
Applications	Western Blot : 0.1-0.3ug/ml ELISA (peptide) LOD : 1:32000
Limitations	This MYC Associated Factor X Antibody / MAX Antibody is available for research use only.
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Description

MYC Associated Factor X Antibody / MAX Antibody recognizes MYC Associated Factor X (MAX), a ubiquitously expressed basic helix-loop-helix leucine zipper transcription factor that serves as the principal dimerization partner for MYC family proteins. The name MYC Associated Factor X reflects the protein's defining biological role as a binding partner that enables MYC proteins to recognize E-box DNA sequences and regulate transcription of genes controlling cell growth, proliferation, metabolism, and differentiation. Unlike MYC proteins, which require a partner for stable DNA binding, MAX forms both activating and repressive transcriptional complexes, making it a central regulator of gene expression. A MYC Associated Factor X Antibody is therefore widely used to investigate transcription factor interactions, MYC signaling, and gene regulatory networks.

MYC Associated Factor X functions as the molecular hub of the MYC/MAX/MXD transcriptional network. By forming heterodimers with MYC family proteins, MAX promotes transcriptional activation of genes involved in ribosome biogenesis, nucleotide metabolism, protein synthesis, and cell cycle progression. Conversely, MAX also partners with MXD family members, MNT, MGA, and other transcriptional repressors to antagonize MYC-dependent transcription and maintain normal cellular homeostasis. This dual regulatory capacity allows MYC Associated Factor X to balance proliferative and differentiative signals within the cell. Researchers frequently examine MYC Associated Factor X together with c-MYC, MYCN, MYCL, MXD1, and MNT to better understand transcriptional control during normal development and malignant transformation. A MYC Associated Factor X Antibody is therefore an essential tool for studies of transcription factor biology and oncogenic signaling.

Disruption of MYC Associated Factor X expression or function has been linked to numerous human cancers, including pheochromocytoma, paraganglioma, neuroblastoma, lung cancer, breast cancer, colorectal cancer, and hematologic malignancies. Germline and somatic alterations in MAX can impair transcriptional regulation and contribute to uncontrolled cellular proliferation through dysregulation of MYC signaling pathways. Beyond oncology, MYC Associated Factor X participates in embryonic development, stem cell maintenance, metabolic regulation, and cellular stress responses. Consequently, a MYC Associated Factor X Antibody has become a valuable reagent for investigations spanning cancer biology, developmental biology, transcriptional regulation, metabolism, and signal transduction.

MYC Associated Factor X is routinely analyzed using Western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, chromatin immunoprecipitation, and flow cytometry to evaluate protein expression, nuclear localization, transcription factor complex formation, and DNA-binding activity. Its highly conserved role within MYC regulatory networks makes it an important biomarker for studies of cell fate determination and gene expression. NSJ Bioreagents provides carefully validated antibodies to support these applications across diverse experimental systems. A MYC Associated Factor X Antibody / MAX Antibody provides researchers with a reliable reagent for investigating MYC-dependent transcription, transcription factor complexes, cell cycle regulation, and mechanisms underlying normal physiology and human disease.

Visit our MAX Antibody / MYC Binding Protein Antibody page for additional information about validated antibodies for investigating MAX expression, MYC signaling, transcription factor complexes, and gene regulatory mechanisms.

Application Notes

Optimal dilution of the MYC Associated Factor X Antibody / MAX Antibody should be determined by the researcher.

Immunogen

Amino acids EEPQSRKKLRMEAS were used as the immunogen for this MAX / MYC Associated Factor X antibody.

Storage

Aliquot and store the MAX / MYC Associated Factor X antibody at -20oC.

Alternate Names

MYC Associated Factor X antibody, MAX antibody, Max Protein antibody, MYC Binding Protein antibody

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MYC Associated Factor X Antibody / MAX Antibody (R33757)

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