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Home >> Antibodies >> Mavs Antibody / Ips-1

Mavs Antibody / Ips-1 (RQ6888)

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  Catalog No Formulation Size Price (USD)  
Image RQ6888 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of mouse ANA-1 cells with Mavs antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Mavs antibody.
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Flow cytometry testing of mouse ANA-1 cells with Mavs antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Mavs antibody.
Western blot testing of 1) rat brain, 2) rat heart, 3) L6, 4) mouse brain, 5) mouse HEPA1-6 and 6) mouse C2C12 cell lysate with Mavs antibody. Predicted molecular weight: 51-54 kDa (cleaved), 57 kDa (unmodified), 75 kDa (aggregated).
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q8VCF0
Applications Western blot : 1-2ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Mavs antibody is available for research use only.
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Description

Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.

Application Notes

Optimal dilution of the Mavs antibody should be determined by the researcher.

Immunogen

Recombinant mouse protein (amino acids M1-Q77) was used as the immunogen for the Mavs antibody.

Storage

After reconstitution, the Mavs antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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